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Fig. 4 | BMC Cancer

Fig. 4

From: Circ-SMARCA5 suppresses progression of multiple myeloma by targeting miR-767-5p

Fig. 4

The effects of Circ-SMARCA5 on proliferation and apoptosis of NCI-H929 cells. Circ-SMARCA5 expression was increased in SMARCA5 (+) group compared to Control (+) group but decreased in SMARCA5 (−) group compared with Control (−) group (a). Cell proliferation was reduced in SMARCA5 (+) group compared with Control (+) group but promoted in SMARCA5 (−) group compared with Control (−) group (b). Cell apoptosis rate was increased in SMARCA5 (+) group compared with Control (+) group but decreased in SMARCA5 (−) group compared with Control (−) group (c, d). Comparisons of Circ-SMARCA5 expression, cell proliferation ability and apoptosis rate were by t test, and P < 0.05 was considered significant. *P < 0.05, **P < 0.01, ***P < 0.001. Round dot represented Control (+) group, square represented SMARCA5 (+) group, regular triangle represented Control (−) group, inverted triangle represented SMARCA5 (−) group. Circ-SMARCA5, Circular RNA SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; Control (+), blank overexpression; SMARCA5 (+), Circ-SMARCA5 overexpression; Control (−), blank shRNA; SMARCA5 (−), Circ-SMARCA5 shRNA

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