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Table 3 Changes in body weight, tissue areas and muscle density during 4 months of follow-up, by gender. Fifty-seven patients were included in body composition changes analysis

From: No evidence for changes in skeletal muscle mass or weight during first-line chemotherapy for metastatic colorectal cancer

  Visit LS Means [95% CI] LS Means [95% CI] - Women LS Means [95% CI] - Men
Weight (kg) T0 67.04 [64.42; 69.66] 57.57 [53.89. 61.25] 76.51 [72.83. 80.19]
T2 66.49 [63.86; 69.11] 57.01 [53.33. 60.70] 75.96 [72.28. 79.64]
T4 67.20 [64.57, 69.84] 57.73 [54.04. 61.42] 76.68 [72.99. 80.37]
SMM (cm2) T0 127.83 [122.47; 133.19] 99.23 [91.96; 106.51] 156.42 [149.14; 163.70]
T2 127.17 [121.74; 132.59] 98.57 [91.26; 105.89] 155.76 [148.43; 163.10]
T4 130.36 [124.60; 136.12] 101.76 [94.11; 109.42] 158.95 [151.45; 166.45]
SMD (HU) T0 40.20 [37.84; 42.56] 39.90 [36.56; 43.23] 40.51 [37.17; 43.85]
T2 40.27 [37.84; 42.71] 40.29 [36.91; 43.67] 40.26 [36.76; 43.76]
T4 37.18 [34.41; 39.94] 33.52 [29.38; 37.65]a 40.86 [37.16; 44.51]
VAT (cm2) T0 99.86 [83.92; 115.80] 59.77 [37.58; 81.96] 139.95 [117.76; 162.14]
T2 102.48 [86.48; 118.47] 62.39 [40.16; 84.61] 142.57 [120.33; 164.80]
T4 108.56 [92.15; 124.96] 68.46 [45.84; 91.09] 148.65 [126.22; 171.07]
SAT (cm2) T0 137.32 [122.65; 152.00] 139.30 [118.57; 160.03] 135.34 [114.57; 156.11]
T2 134.95 [120.23; 149.67] 134.74 [113.98; 155.51] 135.15 [114.29; 156.01]
T4 132.75 [117.69; 147.80] 123.85 [102.34; 145.36]b 141.64 [120.58; 162.70]
  1. For each body component, the fitted model contained only gender and visit
  2. LS lean square means, CI Confidence Interval, SMM skeletal muscle mass index (cm2), SMD skeletal muscle density, HU Hounsfield Unit, VAT visceral adipose tissue (cm2), SAT subcutaneous adipose tissue (cm2)
  3. aP = 0.038; bP = 0.030