Table 1 Patient, tumor, treatment and body composition characteristics at inclusion
Male n = 38 (50%) | Female n = 38 (50%) | Total n = 76 | P-value | |
|---|---|---|---|---|
Age (years) | 60.7 ± 9.1 | 60.5 ± 11.0 | 60.6 ± 10.0 | 0.971 |
ECOG-PS | 1.000 | |||
0–1 | 35 (92%) | 34 (90%) | 69 (91%) | |
2 | 3 (8%) | 4 (10%) | 7 (9%) | |
Tumor type | 1.000 | |||
colon | 31 (82%) | 31 (82%) | 62 (82%) | |
rectum | 7 (18%) | 7 (18%) | 14 (18%) | |
Number of metastatic sites | 0.479 | |||
1 | 13 (34%) | 16 (42%) | 29 (38%) | |
≥ 2 | 25 (66%) | 22 (58%) | 47 (62%) | |
Treatment regimen | 0.163 | |||
XELIRI | 19 (50%) | 13 (34%) | 32 (42%) | |
FOLFIRI | 19 (50%) | 25 (66%) | 44 (58%) | |
Weight (kg) | 76.4 ± 12.3 | 57.7 ± 10.8 | 67.0 ± 14.8 | < 0.001 |
Weight loss (WL) (%) | 6.0 ± 6.0 | 6.0 ± 7.9 | 6.0 ± 7.0 | 0.564 |
WL category 5% cut-off | 0.386 | |||
≤ 5% | 19 (58%) | 14 (44%) | 33 (51%) | |
> 5% | 14 (42%) | 18 (56%) | 32 (49%) | |
Missing | 5 (−) | 6 (−) | 11 (−) | |
WL category 10% cut-off | 0.941 | |||
≤ 10% | 25 (76%) | 23 (72%) | 48 (74%) | |
> 10% | 8 (24%) | 9 (28%) | 17 (26%) | |
Missing | 5 (−) | 6 (−) | 11 (−) | |
BMI (kg/m2) | 25.6 ± 3.8 | 22.3 ± 4.1 | 23.9 ± 4.2 | < 0.001 |
BMI category (kg/m2) | 0.001 | |||
< 18.5 | 0 (0%) | 7 (18%) | 7 (9%) | |
18.5–24.9 | 16 (42%) | 22 (58%) | 38 (50%) | |
25–29.9 | 15 (40%) | 8 (21%) | 23 (30%) | |
≥ 30 | 7 (18%) | 1 (3%) | 8 (11%) | |
SMM index (cm2/m2) | 52.9 ± 9.9 | 37.9 ± 5.4 | 45.4 ± 10.9 | < 0.001 |
SMD (HU) | 40.4 ± 8.9 | 40.0 ± 11.2 | 40.2 ± 10.0 | 0.881 |
VAT index (cm2/m2) | 46.5 ± 28.0 | 23.8 ± 20.5 | 35.1 ± 26.9 | < 0.001 |
SAT index (cm2/m2) | 45.6 ± 17.5 | 54.2 ± 30.5 | 50.0 ± 25.2 | 0.285 |
SMM depletion | 12 (32%) | 28 (74%) | 40 (53%) | < 0.001 |