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Table 1 Amino acid changes in Rhabdomyosarcomatous dedifferentiation of GIST as reported in the literature

From: Case report of rhabdomyosarcomatous transformation of a primary gastrointestinal stromal tumor (GIST)

Morphologya (dedifferentiated) Mutation Amino Acid Change Reference
Rhabdomyosarcomatousb 6 nt deletion KV558–559del and Trp557Phe our sample
Rhabdomyosarcomatousb 6 nt deletion KV558–559 Jiang 2015 [14]
Rhabdomyosarcomatous Missense V559D Zheng 2013 [15]
Rhabdomyosarcomatous Missense V559D Liegl 2009 case 1 [2]
Rhabdomyosarcomatous 18 nt deletion 556–574 del Liegl 2009 case 2 [2]
Rhabdomyosarcomatous Missense V559D Liegl 2009 case3 [2]
Rhabdomyosarcomatous 54 nt deletion 556–574 del Liegl 2009 case 4 [2]
Rhabdomyosarcomatous none PDGFRA exon 18 del Liegl 2009 case 5 [2]
  1. aMorphology: the morphologic findings of dedifferentiated component after TKIs treatment in the metastatic sites and non-metastatic sites including our caseb