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Fig. 2 | BMC Cancer

Fig. 2

From: Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas

Fig. 2

Kaplan-Meier survival analysis for COL3A1, GPR158 and PITHD1. Kaplan-Meier plots illustrating the probability of OS and DSS according to dichotomized protein expression of COL3A1 (a-b), GPR158 (c-d) and PITHD1 (e-f). Patients with COL3A1-positive protein expression revealed an association with shorter OS (P value = 0.026). GRP158-positive and PITHD1-negative protein expression showed both significantly shorter OS and DSS times (GPR158 OS P value = 0.00043, DSS P value 0.029; PITHD1 OS P value = 0.012, DSS P value = 0.003). The x-axes depict OS or DSS and the y-axes depict days after initial diagnosis. Hazard ratio (HR), 95% confidence interval, log rank P value were calculated using Cox proportional hazard model and log-rank tests, respectively

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