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Table 1 Characteristics of advanced pancreatic cancer patients with baseline and week-6 measurements

From: CA19–9 decrease and survival according to platelet level in patients with advanced pancreatic cancer

Characteristic*

N = 200

Age

 Median, IQR

55 (50–62)

Sex (Male/Female)

 Male

127 (63.5%)

 Female

73 (36.5%)

KPS

 90–100

169 (84.5%)

 70–80

31 (15.5%)

Prediagnosis body mass index

 Median, IQR

22.8 (21.0–25.0)

Diabetes Mellitus

 Absent

152 (76.0%)

 Present

48 (24.0%)

Location

 Head/Uncinate

73 (36.5%)

 Body/tail

124 (62.0%)

 Overlapping sites

3 (1.5%)

Stage

 III

22 (11.0%)

 IV

178 (89.0%)

Liver metastasis

 Absent

53 (26.5%)

 Present

147 (73.5%)

Baseline CA19–9, U/ml

 Median, IQR

1364.5 (203.6–9094.3)

CA19–9 change†

 Median, IQR

−0.22 ([− 0.60]-0.088)

Baseline Platelet (×109/L)

 Median, IQR

195 (153.0–235.3)

Chemotherapy regimen

 Gemcitabine monotherapy

34 (17.0%)

Gemcitabine plus 5-Fu

18 (9.0%)

Gemcitabine plus nab-PTX

16 (8.0%)

Gemcitabine plus DDP

9 (4.5%)

Nab-PTX plus S-1‡

123 (61.5%)

Radiotherapy

 Yes

16 (8.0%)

 No

184 (92.0%)

  1. * Percentage indicates the proportion of patients with a specific clinical, pathologic, or molecular characteristic among all patients
  2. † CA19–9 change = ([CA19–9 at week-6]-[CA19–9 at baseline]) / (CA19–9 at baseline)
  3. Abbreviations: KPS, Karnofsky Performance Status; IQR, Inter Quartile Range
  4. ‡ This chemothrapy regimen is a phase II clincial trial conducted in our institute (NCT02124317)