Skip to main content

Table 2 Multivariate Cox proportional hazards regression analysis of the development cohort

From: Nomograms for predicting survival in patients with metastatic gastric adenocarcinoma who undergo palliative gastrectomy

  Postoperative Model Preoperative Model
HR a 95% CI b P HR 95% CI P
Age (“≤65”as reference)    0.004    0.000
 66–80 1.075 0.935–1.236 0.311 1.285 1.123–1.470 0.000
 >80 1.391 1.143–1.694 0.001 1.977 1.643–2.378 0.000
Sex (“Male” as reference)
 Female 0.961 0.843–1.095 0.548 0.990 0.869–1.129 0.885
Race (“White” as reference)    0.600    0.593
 Black 0.984 0.823–1.177 0.863 0.962 0.805–1.148 0.665
 Other 0.923 0.789–1.079 0.313 0.923 0.791–1.078 0.314
Tumor location (“Cardia” as reference)    0.008    0.020
 Non-cardia 0.816 0.684–0.974 0.024 0.935 0.785–1.113 0.449
 Overlapping lesion 1.054 0.829–1.340 0.669 1.241 0.977–1.577 0.077
 Stomach, NOSc 1.014 0.784–1.312 0.915 1.129 0.876–1.455 0.348
Tumor size (“≤30 mm” as reference)    0.033    0.041
 31-50 mm 0.985 0.802–1.209 0.882 1.120 0.914–1.373 0.273
  > 50 mm 0.833 0.684–1.014 0.069 0.938 0.773–1.138 0.515
Subtype (“Intestinal type” as reference)    0.536    0.267
 Diffuse type 0.861 0.664–1.117 0.260 0.925 0.717–1.193 0.547
 Adenocarcinoma, NOS 0.997 0.846–1.175 0.972 1.095 0.932–1.287 0.269
 Other adenocarcinoma 0.906 0.708–1.159 0.431 0.943 0.738–1.206 0.642
Grade (“Grade1/2” as reference)
 Grade3/4 1.334 1.155–1.540 0.000 1.269 1.100–1.463 0.001
T category-AJCCd 7th (“T1” as reference)    0.000    0.000
 T2 1.395 0.894–2.179 0.143 1.252 0.803–1.953 0.321
 T3 1.906 1.341–2.708 0.000 1.658 1.171–2.348 0.004
 T4a 2.284 1.594–3.273 0.000 1.971 1.382–2.811 0.000
 T4b 2.457 1.704–3.542 0.000 2.128 1.481–3.058 0.000
N category-AJCC 7th (“N0” as reference)    0.000    
 N1 1.341 1.082–1.662 0.007
 N2 2.003 1.579–2.542 0.000
 N3 2.128 1.617–2.801 0.000
 N+ 1.397 1.137–1.717 0.001
Metastatic site(s) (“Distant LN(s)e” as reference)    0.000    0.000
 Viscera 1.496 1.255–1.783 0.000 1.586 1.334–1.886 0.000
 Viscera plus distant LN(s) 1.810 1.389–2.359 0.000 1.782 1.372–2.314 0.000
 Distant metastasis, NOS 1.748 1.223–2.497 0.002 1.664 1.173–2.362 0.004
Gastrectomy (“Partial gastrectomy” as reference)    0.078    
 Near-total or total gastrectomy 0.838 0.718–0.978 0.025
 Gastrectomy, NOS 0.930 0.801–1.080 0.343
No. of regional LN(s) examined (“≤10” as reference)
 > 10 0.684 0.591–0.792 0.000
Surgery to other site(s) or node(s) (“No” as reference
 Yes 1.008 0.877–1.159 0.913
Chemotherapy (“No/Unknown” as reference
 Yes 0.514 0.448–0.589 0.000
Radiotherapy (“No/Unknown” as reference
 Yes 0.778 0.647–0.936 0.008
  1. ahazard ratio; bconfidence interval; cnot otherwise specified; dAmerican Joint Committee on Cancer; elymph node(s)