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Table 2 Multivariable covariate-adjusted Cox models for colorectal cancer-specific survival

From: Impact of prior malignancies on outcome of colorectal cancer; revisiting clinical trial eligibility criteria

Patient characteristics Colorectal cancer–specific HRa (95% CI)b Colorectal cancer–specific P valuec
Prior cancer diagnosis (vs none)
 Prior non-leukemic malignancies .930 (.909 to .952) <.001
 Prior leukemias 1.263 (1.116 to 1.430) <.001
Age (vs 20–65), y
 < 20 .931 (.748 to 1.158) .531
 > 65 1.376 (1.361 to 1.392) <.001
Sex (vs female)
 Male 1.124 (1.112 to 1.136) <.001
Race (vs white)
 Black 1.135 (1.116 to 1.154) <.001
 Others .872 (.854 to .890) <.001
Marital status (vs single)
 Married .895 (.880 to .910) <.001
 Separated 1.116 (1.066 to 1.168) <.001
 Divorced .942 (.920 to .965) <.001
 Widowed 1.108 (1.087 to 1.129) <.001
Stage (VS Localized)
 Regional 2.983 (2.937 to 3.029) <.001
 Distant 13.548 (13.331 to 13.769) <.001
Grade (Vs Well Differentiated)
 Moderately Differentiated 1.153 (1.132 to 1.174) <.001
 Poorly Differentiated 1.668 (1.634 to 1.701) <.001
 Undifferentiated and Anaplastic 1.904 (1.828 to 1.983) <.001
Radiation (Vs No)
 Yes 1.019 (1.004 to 1.034) .011
Surgery (Vs No)
 Yes .434 (.427 to .442) <.001
 Ablation 1.058 (.918 to 1.219) .435
  1. athis number represent the hazard ratio for all cause and colorectal cancer specific death for the above coverables. All statistical tests were tow-sided
  2. bthis represents confidence interval
  3. cTwo-sided P value was calculated from multivariable covariate-adjusted Cox models