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Table 1 Baseline Characteristics and Demographics of Patients

From: Sites of metastasis and association with clinical outcome in advanced stage cancer patients treated with immunotherapy

 

n (%)

Gender

 Male

53 (58.9)

 Female

37 (41.1)

Race

 White

70 (77.8)

 Black

16 (17.8)

 Asian/Unknown

4 (4.4)

Histology

 Melanoma

30 (33.3)

 Gastrointestinal

20 (22.2)

 Lung, Head & Neck

18 (20.0)

 Breast

11 (12.2)

 Gynecological cancers

3 (3.3)

 Genitourinary cancers

3 (3.3)

 Others

5 (5.6)

Number of metastatic sites

 1

24 (26.7)

 2

33 (36.7)

 3+

33 (36.7)

Sites of metastases

 Lymph node

58 (64.4)

 Liver

40 (44.4)

 Lung

37 (41.1)

 Bone

24 (26.7)

 Brain

8 (8.9)

ECOG PS

 0

34 (38.2)

 1

55 (61.8)

RMH Risk Group

 Good

71 (80.7)

 Poor

17 (19.3)

Checkpoint Indication

 Yes

49 (54.4)

 No

41 (45.6)

Treatment Regimen

 Anti-PD-L1 Monotherapy

25 (27.8)

 FDA-approved IO + Experimental IO

46 (51.1)

 Experimental IO Monotherapy

19 (21.1)

Number of prior systemic therapies in the metastatic setting

 0–1

28 (31.1)

 2+

62 (68.9)

Prior treatment with ICB

 Yes

27 (30.0)

 No

63 (70.0)

  1. ECOG PS Eastern Cooperative Oncology Group performance status, RMH Royal Marsden Hospital, IO Immunotherapy, PD-L1 Programmed death ligand 1, ICB Immune checkpoint blocker