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Fig. 8 | BMC Cancer

Fig. 8

From: Ubiquitous expressed transcript promotes tumorigenesis by acting as a positive modulator of the polycomb repressive complex 2 in clear cell renal cell carcinoma

Fig. 8

High expression of UXT is associated with advanced TNM stage and poor prognosis in patients with ccRCC. a Real-time quantitative PCR showed that UXT expression is increased in ccRCC patient tissue. b UXT mRNA levels in ccRCC patients downloaded from TCGA archive. Differential expression between ccRCC and normal tissues was calculated by using the downloaded RSEM (RNA-Seq by Expectation Maximization) values. c UXT is highly expressed in ccRCC patients with advanced TNM stage (III/IV stage). d UXT expression is negatively correlated with DAB2IP (P < 0.0001, r2 = 0.03686). e-g Clinical survival outcomes of ccRCC patients with high UXT expression (N = 246) or low UXT expression (n = 245). OS (e), DSS (f), and PFI (g). High expression of UXT is associated with poor prognosis in patients with ccRCC

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