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Fig. 1 | BMC Cancer

Fig. 1

From: Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p

Fig. 1

GRM4 is a potential biomarker for breast cancer. a. Heatmap displays the mRNA expression patterns of eight family members of GRM in four subtypes of breast cancer. b. The mRNA expression levels of GRM4 in 8 breast cancer tissues and 10 non-tumor tissues were measured by qPCR. c. GRM4 mRNA expression levels in six breast cancer cell lines and mammary epithelial cell MCF10A were measured by qPCR. d The protein expression levels of GRM4 in 15 breast cancer tissues and 10 control tissues were measured by immunohistochemistry (IHC). Representative images are shown on the left. e. Kaplan–Meier analysis compared the overall survival between breast cancer patients with high GRM4 expression and low GRM4 expression. P<0.001 by long rank test

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BMC Cancer

ISSN: 1471-2407

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