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Table 6 Comparison of ROC Curves for Expression of miRNA in Plasma between CIN1- and CIN2+

From: Plasma expression of miRNA-21, − 214, −34a, and -200a in patients with persistent HPV infection and cervical lesions

Area Under the Curve (AUC)
Test Result Variable (s) Area Std. Errora Asymptotic Sig.b Asymptotic 95% Confidence Interval
Lower Bound Upper Bound
miRNA-21 .613 .069 .113 .477 .749
miRNA-34a .508 .067 .908 .377 .639
miRNA-200a .615 .082 .108 .455 .775
miRNA-214 .505 .084 .941 .340 .670
  1. The test variable(s): plasma expression levels of miRNA exhibited at least one tie between CIN1- and CIN2+ patients. The AUC values for miRNA-21, −34a, −200a and − 214 were 0.613, 0.508, 0.615 and 0.505, respectively
  2. aUnder the nonparametric assumption
  3. bNull hypothesis: true area = 0.5