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Table 6 Comparison of ROC Curves for Expression of miRNA in Plasma between CIN1- and CIN2+

From: Plasma expression of miRNA-21, − 214, −34a, and -200a in patients with persistent HPV infection and cervical lesions

Area Under the Curve (AUC)

Test Result Variable (s)

Area

Std. Errora

Asymptotic

Sig.b

Asymptotic 95% Confidence Interval

Lower Bound

Upper Bound

miRNA-21

.613

.069

.113

.477

.749

miRNA-34a

.508

.067

.908

.377

.639

miRNA-200a

.615

.082

.108

.455

.775

miRNA-214

.505

.084

.941

.340

.670

  1. The test variable(s): plasma expression levels of miRNA exhibited at least one tie between CIN1- and CIN2+ patients. The AUC values for miRNA-21, −34a, −200a and − 214 were 0.613, 0.508, 0.615 and 0.505, respectively
  2. aUnder the nonparametric assumption
  3. bNull hypothesis: true area = 0.5