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Table 1 Clinical, biochemical characteristics and radiation planning parameters of patients enrolled in this study

From: Biologically effective dose (BED) of stereotactic body radiation therapy (SBRT) was an important factor of therapeutic efficacy in patients with hepatocellular carcinoma (≤5 cm)

Variables

n

Clinical and biochemical characteristics

 Sex

  Male

80 (74.07%)

  Female

28 (25.93%)

 Age (years)

  Median

54

  Range

37–77

 Underlying liver disease

  Hepatitis B

97 (89.81%)

  Hepatitis C

7 (6.48%)

  Alcoholic hepatitis

3 (2.78%)

  None

1 (0.93%)

 Maximum tumor diameter (cm)

  Median

2.3

  Range

0.7–4.9

 AFP (ng/ml) a

  Median

33.13

  Range

0.8–7896

 Child-Pugh score

  5

97 (89.81%)

  6

11 (10.19%)

 ALBI grade

  Grade 1

34 (31.48%)

  Grade 2

74 (68.52%)

 WBC count (×109/L)

  Median

4.86

  Range

1.53–9.4

 PLT count (×109/L)

  Median

118

  Range

50–283

 Radiation planning parameters

 Isodose line of maximum dose

  Median (range, %)

72 (60–86)

 Residual normal liver volume

  Median (range, cm3)

1324 (834–2493)

 Mean dose of whole liver volume minus GTV

  Median (range, Gy)

9.07 (4.04–12.05)

 Dose received by volume of liver

 D700c

4.99 (1.40–13.50)

 BED10b of Plan target volume (PTV)

  Median (range, Gy)

100 (76.8–102.6)