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Table 2 Genes differentially expressed between metaplastic breast cancer and invasive ductal triple negative breast cancer samples

From: Pathway activity profiling of growth factor receptor network and stemness pathways differentiates metaplastic breast cancer histological subtypes

Gene Log2 Fold Change p-value FDR-adjusted p-value
Genes upregulated in metaplastic samples
 PTHLH 4.11 1.90E-05 4.43E-04
 IGFBP3 1.97 6.59E-05 1.23E-03
 ICAM1 1.71 6.57E-04 8.83E-03
 IER3 1.72 8.62E-04 1.07E-02
 BST2 1.56 1.23E-03 1.43E-02
 HAS2 1.93 2.48E-03 2.45E-02
 PDPN 1.95 2.47E-03 2.45E-02
 IL6 2.31 2.64E-03 2.54E-02
 COL5A1 1.52 3.86E-03 3.12E-02
 FN1 1.53 3.59E-03 3.12E-02
 IL8 2.02 4.87E-03 3.80E-02
 PLAT 1.77 5.52E-03 3.99E-02
 COL5A2 1.52 5.77E-03 4.04E-02
 COL1A1 1.67 5.93E-03 4.07E-02
 INHBA 1.49 6.65E-03 4.47E-02
 CDH11 1.15 7.22E-03 4.53E-02
 MYLK 1.32 7.13E-03 4.53E-02
 CTGF 1.37 7.31E-03 4.53E-02
Genes downregulated in metaplastic samples
 PRR9 −5.10 2.55E-15 8.58E-13
 LCE3E −31.84 3.33E-14 5.60E-12
 LCE1F −5.76 1.43E-11 1.60E-09
 FAM25A −3.87 2.89E-10 2.43E-08
 AGPAT9 −2.65 5.29E-10 3.45E-08
 DUSP8 −2.14 6.17E-10 3.45E-08
 FAM83A-AS1 −3.61 4.15E-08 1.99E-06
 FGFBP2 −0.26 1.20E-07 5.06E-06
 CHAC1 −2.84 3.57E-07 1.33E-05
 HSPE1 − 2.07 1.10E-06 3.69E-05
 CD24 −2.90 1.57E-06 4.80E-05
 ALOXE3 −3.54 4.81E-06 1.35E-04
 ERBB2 −1.24 1.22E-05 3.16E-04
 RIMS3 −1.36 1.98E-05 4.43E-04
 ACTBL2 −3.04 2.11E-05 4.44E-04
 KLK6 −3.51 3.69E-05 7.30E-04
 LCE3D −4.12 8.55E-05 1.51E-03
 ABCB1 −2.20 1.15E-04 1.94E-03
 LOC100130238 −2.86 2.12E-04 3.39E-03
 BMP6 −2.06 4.06E-04 6.19E-03
 TMCC2 −1.55 5.38E-04 7.86E-03
 LEP −2.77 6.05E-04 8.47E-03
 ZSCAN12P1 −1.70 8.46E-04 1.07E-02
 CCL26 −1.96 9.29E-04 1.11E-02
 MAL −2.26 1.38E-03 1.54E-02
 ERBB3 −1.85 2.29E-03 2.41E-02
 NOV −1.52 2.26E-03 2.41E-02
 PAPL −1.91 2.88E-03 2.69E-02
 DSCAM −2.87 3.76E-03 3.12E-02
 KRT81 −2.34 3.69E-03 3.12E-02
 TAGLN3 − 2.02 3.90E-03 3.12E-02
 ZNF165 −1.39 3.44E-03 3.12E-02
 CALML5 −2.55 5.00E-03 3.82E-02
 DIRAS3 −1.69 5.52E-03 3.99E-02
 ARHGAP33 −0.66 5.58E-03 3.99E-02
 RASD2 −1.24 6.92E-03 4.53E-02
 FAM46B −1.20 7.41E-03 4.53E-02
 PDGFB −0.79 8.17E-03 4.90E-02
  1. FDR false-discovery rate