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Fig. 3 | BMC Cancer

Fig. 3

From: Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer

Fig. 3

Effectiveness of HER-2/HER-3 inhibition combined with 5-FU and oxaliplatin. Cellular viability of LS513, LS1034, and SW837 cells was assessed 24 h (black curve), 48 h (red curve), and 72 h (blue curve) after treatment with 5-FU and oxaliplatin combined with trastuzumab (a), pertuzumab (b), T-DM1 (c), lapatinib (d), and afatinib (e). All experiments were performed in triplicate, independently repeated three times. The respective P-values and the (estimated) EC50 for all drugs and time points are listed in Additional file 5: Table S1

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BMC Cancer

ISSN: 1471-2407

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