Table 1 Genetic alterations of SMARCB1 in the AT/RT samples
From: NPM1 as a potential therapeutic target for atypical teratoid/rhabdoid tumors
Patient | Copy number alteration | Somatic mutation (type) | aRelative expression level |
|---|---|---|---|
P1 | Heterozygous deletion | c.811G > T (stop codon, homozygote) | −3.76 |
P2 | Homozygous deletion | Not available | −3.42 |
P3 | Copy neutral | c.118C > T (stop codon, homozygote) | −2.22 |
P4 | Heterozygous deletion | c.93 + 2 T > C (splice donor, heterozygote) | −2.51 |