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Table 1 Relative expression and prognosis of sox family genes in the training cohort (TCGA-LIHC cohort I, n = 188)

From: Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma

Gene

Expression

Overall survival

Mean normalized expression

Trend

P Valuea

Mean OS time (months)

P Value#

HCC

Normal liver

Low expression

High expression

SOX1

0.2995

0.1106

Up

0.2784

996

816

0.741

SOX2

2.0960

0.7323

Up

0.0001

1017

915

0.704

SOX3

0.0967

0

Up

0.0001

1019

493

0.000

SOX4

8.9210

8.2760

Up

0.0172

1109

802

0.005

SOX5

5.8270

7.1320

Down

0.0001

913

1012

0.801

SOX6

6.6730

8.7640

Down

0.0001

1027

906

0.747

SOX7

6.4660

7.3970

Down

0.0001

906

976

0.267

SOX8

2.3920

2.3090

Up

0.7006

895

1019

0.225

SOX9

8.7280

8.2970

Up

0.2150

995

928

0.609

SOX10

0.8675

2.5260

Down

0.0001

1055

861

0.092

SOX11

1.5660

0.3328

Up

0.0001

1120

790

0.001

SOX12

9.2010

8.0270

Up

0.0001

1017

910

0.010

SOX13

10.2500

9.4920

Up

0.0001

971

924

0.138

SOX14

0.1806

0

Up

0.0001

1002

630

0.019

SOX15

2.7610

2.5210

Up

0.0562

930

996

0.261

SOX17

5.7740

5.6750

Up

0.5462

859

1054

0.019

SOX18

7.8070

7.1120

Up

0.0001

930

963

0.121

SOX21

0.8787

0.1807

Up

0.0019

1013

883

0.059

SOX30

0.8157

0.7922

Up

0.8675

929

974

0.692

  1. a, Unpaired student t test
  2. #, Kaplan Meier survival Log-rank P value
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BMC Cancer

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