Fig. 4

The prognostic significance of SOX signature genes in multiple HCC clinical cohorts. a The patients in the training set (TCGA-LIHC Cohort I, n = 188) were divided into “High sox group” and “Low sox group” according to the SOX signature score. Kaplan–Meier survival curves of the two risk groups were plotted and the log-rank P value of the survival difference calculated between them (Upper panel). Kaplan–Meier survival curves of HCC patients from subgroups with different SOX signature score (Lower panel). b Similar analysis was down in the testing set (TCGA-LIHC Cohort II, n = 189). c and validated in an independent validation set (LIRI-JP Cohort, n = 232). P value less than 0.05 was considered statistically significant. The figures were generated using SPSS v19