Skip to main content
Fig. 4 | BMC Cancer

Fig. 4

From: FBXW7 circular RNA regulates proliferation, migration and invasion of colorectal carcinoma through NEK2, mTOR, and PTEN signaling pathways in vitro and in vivo

Fig. 4

Levels of NEK2, mTOR, and PTEN mRNAs and proteins were determined by qRT-PCR and western blot in tumor tissues. Effect of circ-FBXW7 on mRNA expressions of NEK2 (a), mTOR (b) and PTEN (c) as well as the them proteins expression (d) and quantitative analysis (e) in SW480 tumor. Overexpressed circ-FBXW7 could repressed the NEK2 and mTOR expressions but improved PTEN expression. Circ-FBXW7 showed similar effect on mRNA expressions of NEK2 (f), mTOR (g) and PTEN (h) as well as the proteins (i and j) in SW620 tumor tissues. Data are expressed as mean ± SD. * p < 0.05 vs. WT group

Back to article page