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Table 2 Comparison of Clinical and CT imaging Characteristics between Type 1 AIP Patients with and without PaT

From: Pancreatic tumor in type 1 autoimmune pancreatitis: a diagnostic challenge

  AIP (n = 69) AIP + PaC (n = 5) P Value
Male 58 (84%) 2 (40%) 0.044
Age (year) 61 (24–80) 58 (42–76) 0.845
Surveillance period (month) 5 (1–109) 3 (0–6) 0.086
IgG4 (n = 65)    0.561
 <1 time upper limit 8 (14%) 1 (20%)  
 1–2 times upper limit 11 (17%) 0 (0%)  
  ≥ 2 times upper limit 41 (69%) 4 (80%)  
CA-199 (n = 65, U/ml) 19.5 (2.0–1987.0) 21.4 (2.0–106.0) 0.767
Biopsy at the initial visit 41 (58%) 5 (100%) 0.150
Presence of extrapancreatic involvement
 Bile duct 63 (91%) 3 (60%) 0.087
 Kidney 25 (36%) 0 (0%) 0.160
 Retroperitoneum 9 (9%) 2 (40%) 0.157
CT imaging characteristics of pancreatic parenchyma
 Enlargement pattern    0.003
  Diffuse 49 (71%) 0 (0%)  
  Focal 20 (29%) 5 (100%)  
 Presence of atrophy 10 (15%) 1 (20%) 0.564
 Presence of heterogeneity 28 (41%) 5 (100%) 0.015
 Presence of low-density (n = 26) 21 (30%) 5 (100%) 0.004
  Mass-like low-density 6 (29%) 4 (80%) 0.055
  Relative density of low-density
   Arterial phase    1.000
    Hypoattenuating 21 (100%) 5 (100%)  
    Isoattenuating 0 (0%) 0 (0%)  
    Hyperattenuating 0 (0%) 0 (0%)  
   Venous phase    0.562
    Hypoattenuating 14 (67%) 4 (80%)  
    Isoattenuating 7 (33%) 1 (20%)  
    Hyperattenuating 0 (0%) 0 (0%)  
  Absolute density of low-density (Hu)
   Pre-enhanced phase 42 (33–53) 45 (28–45) 0.769
   Arterial phase 71 (51–96) 53 (32–89) 0.313
   Venous phase 83 (57–112) 81 (37–94) 0.255
CT imaging characteristics of main pancreatic duct
 Presence of dilatation 16 (23%) 1 (20%) 1.000
 Presence of cutoff 31 (45%) 2 (40%) 1.000
CT imaging characteristics of peripancreatic structures
 Presence of halo sign 43 (62%) 2 (40%) 0.374
 Presence of stranding 14 (20%) 3 (60%) 0.076
 Presence of ascites 2 (3%) 1 (20%) 0.192
 Presence of vessel stricture 44 (64%) 4 (80%) 0.651
  1. Abbreviations: AIP autoimmune pancreatitis, PaT pancreatic tumor, Hu Hounsfield
  2. Quantitative data are expressed as median (range), qualitative data as absolute values (percentages)