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Table 1 Summary of Clinical and CT Imaging Characteristics of Type 1 AIP Patients with PaT

From: Pancreatic tumor in type 1 autoimmune pancreatitis: a diagnostic challenge

   PDAC (n = 3)   SEP (n = 1) CCa (n = 1)
Case 1a Case 2 Case 3   
Gender Male Male Female Female Female
Surveillance period (month) 3 0 0 3 6
IgG4 (≤2 g/L, g/L) 6.9 5.2 4.6 0.3 4.1
CA-199 (0-35 U/ml, U/ml) 64.7 14.6 106.0 2.0 21.4
Biopsy at initial visit
 Location Pancreas Pancreas Pancreas Pancreas Pancreas
 Evidence of PaT No Yes Yes No No
Presence of extrapancreatic involvement
 Bile duct No No Yes Yes Yes
 Kidney No No No No No
 Retroperitoneum No Yes No Yes No
CT imaging characteristics of pancreatic parenchyma
 Focal enlargement Yes Yes Yes Yes Yes
 Presence of atrophy No No Yes No No
 Presence of heterogeneity Yes Yes Yes Yes Yes
 Presence of low-density Yes Yes Yes Yes Yes
  Mass-like Yes Yes Yes No Yes
  Relative density
   Arterial phase Hypo Hypo Hypo Hypo Hypo
   Venous phase Hypo Hypo Hypo Hypo Iso
  Absolute density (Hu)
   Pre-enhanced phase 38 45 28 45 45
   Arterial phase 53 51 32 76 89
   Venous phase 68 81 37 94 94
CT imaging characteristics of main pancreatic duct
 Dilatation Yes No No No No
 Cutoff Yes No Yes No No
CT imaging characteristics of peripancreatic structures
 Presence of halo sign Yes No No Yes No
 Presence of stranding Yes No Yes Yes No
 Presence of ascites No No No Yes No
 Presence of vessel stricture Yes Yes Yes Yes No
  1. Abbreviations: AIP autoimmune pancreatitis, PaT pancreatic tumor, PDAC pancreatic ductal adenocarcinoma, SEP solitary extramedullary plasmacytoma, CC cholangiocarcinoma, Hypo hypoattenuating, Iso Isoattenuating, Hu Hounsfield
  2. a Marked cases underwent pancreatic resection, and the presence of concurrent PaT in other unmarked cases were proved by biopsy at the initial visit or in the surveillance period