Fig. 8From: Human bronchial carcinoid tumor initiating cells are targeted by the combination of acetazolamide and sulforaphaneBronchial carcinoid tumor patient-derived spheroids show high tumorigenic potential both orthotopically and subcutaneously. a Shows the gross morphology of normal lung (left) and the patient-derived orthotopic tumor (right) in lung (arrows); b H&E histology at lower and higher magnifications of the patient-derived tumor showing typical BC morphology and dense cellularity; c Immunofluorescence labeling for Chromogranin A (ChA) in patient derived orthotopic lung xenograft. DAPI counterstain for labeling of cell nuclei. d Gross morphology of patient derived subcutaneous xenografts (arrows) in mouse subinguinal region. e H&E histology of the resected subcutaneous xenograft; f Immunohistochemical staining for Chromogranin A in subcutaneous xenograftsBack to article page