Fig. 5
Spheroid cells demonstrate increased tumorigenic potential. a Magnetic resonance imaging (MRI) was performed on the fifth inguinal mammary fat pad of mice 10 days post-implantation of PA monolayer cells and 3rd generation spheroid (SP) bronchial carcinoid cells (H727 and H720; 3 × 104 cells, n = 5) implantation; b Examination of extirpated tumors (n = 5) by gross morphology; c Tumor volumes measured over 80 days given in cc calculated from caliper measurements; d Tumor weights measured after extirpation given in grams. e H&E histology of the PA and SP cell derived xenografts