Parkin gene mutations are not common, but its epigenetic inactivation is a frequent event and predicts poor survival in advanced breast cancer patients

Table 1 Correlation of Parkin promoter methylation with Parkin protein expression

Parkin Promoter	Parkin expression^a		Total (%)	p Value^b	OR (95%CI)
Parkin Promoter	Negative	Positive	Total (%)	p Value^b	OR (95%CI)
Unmethylated	37 (51)	35 (49)	72 (46)	0.0001*	0.2298 (0.1113–0.4744)
Methylated	69 (82)	15 (18)	84 (54)	0.0001*	0.2298 (0.1113–0.4744)
Total (%)	106 (68)	50 (32)	156 (100)

ISSN: 1471-2407