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Table 1 Correlation of Parkin promoter methylation with Parkin protein expression

From: Parkin gene mutations are not common, but its epigenetic inactivation is a frequent event and predicts poor survival in advanced breast cancer patients

Parkin Promoter Parkin expressiona Total (%) p Valueb OR (95%CI)
Negative Positive
Unmethylated 37 (51) 35 (49) 72 (46) 0.0001* 0.2298 (0.1113–0.4744)
Methylated 69 (82) 15 (18) 84 (54)
Total (%) 106 (68) 50 (32) 156 (100)   
  1. aProtein expression through IHC (Immunohistochemistry)
  2. bFisher’s Exact test, *Significant Correlation (P < 0.05)