Comparison of overall survival and perioperative outcomes of laparoscopic pancreaticoduodenectomy and open pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: a systematic review and meta-analysis

Table 1 Basic Characteristics of the Included Studies

Study	Year	Design	Sample Size		Mean age(years)		Tumor Size(cm)		BMI (kg/m²)		Neoadjuvant therapy (sample size)
Study	Year	Design	LPD	OPD	LPD	OPD	LPD	OPD	LPD	OPD	LPD	OPD
Croome	2014	P,S	108	214	66.6	65.4	3.3^a	3.3^a	27.4^a	27.2^a	12	30
Speicher	2014	R,S	25	84	61	64	2^b	3^b	24^b	25^b	9	26
Sharpe	2015	R,M	384	4037	65.6	66.1	3.2^a	3.3^a	NA	NA	NA	NA
Stauffer	2016	P,S	58	193	66.9	68.9	2.5^b	3.5^b	25.9^b	25.6^b	NA	NA
Champman	2017	R,M	248	1520	79.6	79.5	NA	NA	NA	NA	175	83
Kantor	2017	R,M	828	7385	65.9	65.7	NA	NA	NA	NA	642	5714
Chen	2018	R,S	47	55	63	66	NA	AN	24^a	22.7^a	NA	NA
Dokmak	2015	P,S	46	46	60	63	2.82^a	2.51^a	22.6^a	26.4^a	NA	NA

P prospective study S single center R retrospective study M mutli-centers NA not avaliable BMI body mass index ^aMean ^bMedian

ISSN: 1471-2407