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Fig. 2 | BMC Cancer

Fig. 2

From: Identification of a novel S6K1 inhibitor, rosmarinic acid methyl ester, for treating cisplatin-resistant cervical cancer

Fig. 2

RAME, not RA, inhibits kinase activity of S6K1 in vitro and in vivo. a Structures of RAME and RA. b and c The in vitro kinase assay with RAME (b) or RA (c) was performed in a dose dependent manner using recombinant GST-S6, active S6K1, and cold-ATP. d Quantitative graph of (b and c). e Immunoblotting analysis of HeLa (left) and SiHa (right) cells treated with RAME (80 μM) or RA (80 μM) for 24 h

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