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Fig. 4 | BMC Cancer

Fig. 4

From: Silencing microRNA-330-5p increases MMP1 expression and promotes an invasive phenotype in oesophageal adenocarcinoma

Fig. 4

Silencing miR-330-5p enhances OE33 cell invasion. a The invasive potential of the OE33 miRZIP-330-5p HC was not significantly increased relative to the miRZIP-VC HC in the 24 h matrigel invasion assay. Data are representative of n = 3 independent experiments. Data presented as the mean ± SEM. Statistical analysis was performed using the one-sample t-test; ns, not significant. However, in (b) the invasive potential of the OE33 miRZIP-330-5p SC was significantly increased relative to the miRZIP-VC SC in the more sensitive non-cross-linked collagen invasion assay at 24 h and 48 h. Data are representative of n = 3 independent experiments. Data presented as the mean ± SEM. Statistical analysis was performed using the paired t-test; * p < 0.05

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