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Fig. 6 | BMC Cancer

Fig. 6

From: Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants

Fig. 6

Violin plots based on Kolmogorov-Smirnov test per each group pairing. Two-sided Kolmogorov-Smirnov (KS) tests were carried per gene to test for differences in the distributions of variants between each of the 15 cancer-type pairs (the same variant distributions shown in Fig. 3 for four selected genes). Each panel displays the distribution of resulted p-values across all 18,421 analyzed genes. Red-colored images represent cancer-type pairs originating from different sequencing centers, while blue-colored images represent pairs originating from the same sequencing center. Cancer-type labels are color-coded by sequencing centers, as in all previous figures. The y axis scale is -log10(p-value), where all values above 2.5 were truncated to 2.5 (for visibility)

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