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Fig. 2 | BMC Cancer

Fig. 2

From: Dynamic and unpredictable changes in mutant allele fractions of BRAF and NRAS during visceral progression of cutaneous malignant melanoma

Fig. 2

Mutant allele fraction (MAF) values of driver oncogenes (a: BRAF, b: NRAS) in major metastatic sites as compared with primary melanomas. Data represent mean+/−SD. The difference in BRAF mutant samples (a) is significant in case of: lung, * p = 0.001, adrenal gland, ** p = 0.021, intestinal tract *** p = 0.018, kidney **** p = 0.043, based on Wilcoxon Signed Ranks Test. No significant differences were detected in NRAS mutant tumors (b)

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