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Table 4 Laboratory values at baseline and in the acute and chronic periods following TACE

From: Liver function changes after transarterial chemoembolization in US hepatocellular carcinoma patients: the LiverT study

Laboratory parameter

Patient number, n

Baseline

(value closest to index TACE)

Acute period (highest value)

P-value acute vs baseline

Chronic period (latest value)

P-value chronic vs baseline

Bilirubin, mg/dL

462

     

 Mean (SD)

 

1.5 (1.1)

2.2 (2.9)

2.3 (4.1)

 Median (range)

 

1.2 (0.09–6.9)

1.4 (0.3–37.9)

P < .0001

1.2 (0.2–41.3)

P = .008

Albumin, g/dL

442

     

 Mean (SD)

 

3.2 (0.7)

2.9 (0.7)

3.1 (0.7)

 Median (range)

 

3.3 (1.6–4.9)

2.8 (1.0–4.8)

P < .0001

3.1 (1.4–4.8)

P < .0001

AST, U/L

446

     

 Mean (SD)

 

75.9 (61.5)

152.6 (270.4)

 

88.5 (187.3)

 

 Median (range)

 

62 (11–844)

82 (13–3341)

P < .0001

60 (9–3739)

P = .600

ALT, U/L

441

     

 Mean (SD)

 

59.5 (49.6)

122.1 (266.8)

 

62.1 (82.8)

 

 Median (range)

 

45 (9–450)

60 (7–3198)

P < .0001

42 (7–1122)

P = .08

INR

251

     

 Mean (SD)

 

1.3 (0.4)

1.6 (0.9)

 

1.5 (0.6)

 

 Median (range)

 

1.2 (0.9–3.2)

1.3 (0.9–6.9)

P < .0001

1.2 (0.9–6.9)

P < .0001

  1. Acute period, 0–29 days after TACE; chronic period, 30–90 days after TACE
  2. ALT alanine transaminase, AST aspartate transaminase, INR international normalized ratio, SD standard deviation, TACE transarterial chemoembolization