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Table 1 Liver function thresholds to establish clinically meaningful deterioration after TACE in a real-world setting (primary analysis)

From: Liver function changes after transarterial chemoembolization in US hepatocellular carcinoma patients: the LiverT study

Parameter Deterioration threshold (change from baseline)
Serum total bilirubin Increase of ≥ 50%
Serum albumin Decrease by ≥ 0.3 g/dL
AST Increase of > 25%
ALT Increase of > 25%
INR Increase of ≥ 25%
  1. ALT alanine transaminase, AST aspartate transaminase, INR international normalized ratio, TACE transarterial chemoembolization