Table 4 Most frequent (≥10%) adverse events reported during treatment
Abiraterone acetate plus prednisone (N = 100) | Cabazitaxel plus prednisone (N = 44) | |||||||
|---|---|---|---|---|---|---|---|---|
Adverse event | Mild | Moderate | Severe | Total | Mild | Moderate | Severe | Total |
Asthenia | 16 (16.0) | 14 (14.0) | 1 (1.0) | 31 (31.0) | 14 (31.8) | 8 (18.2) | 2 (4.5) | 24 (54.5) |
Pain | 14 (14.0) | 11 (11.0) | 3 (3.0) | 28 (28.0) | 3 (6.8) | 3 (6.8) | 3 (6.8) | 9 (20.5) |
Anemia | 7 7.0 | 7 7.0 | 1 (1.0) | 15 (15.0) | 6 (13.6) | 3 (6.8) | 1 (2.3) | 10 (22.7) |
Edema | 13 (13.0) | 2 (2.0) | 0 (0.0) | 15 (15.0) | 3 (6.8) | 1 (2.3) | 2 (4.5) | 6 (13.6) |
Vomiting | 7 (7.0) | 0 (0.0) | 2 (2.0) | 9 (9.0) | 4 (9.1) | 1 (2.3) | 0 (0.0) | 5 (11.4) |
Diarrhea | 6 (6.0) | 2 (2.0) | 0 (0.0) | 8 (8.0) | 7 (15.9) | 5 (11.4) | 2 (4.5) | 14 (31.8) |
Anorexia | 6 (6.0) | 1 (1.0) | 0 (0.0) | 7 (7.0) | 5 (11.4) | 3 (6.8) | 1 (2.3) | 9 (20.5) |
Urinary infection | 1 (1.0) | 5 (5.0) | 1 (1.0) | 7 (7.0) | 1 (2.3) | 3 (6.8) | 2 (4.5) | 6 (13.6) |