Fig. 2
From: VEGF-C induced by TGF- β1 signaling in gastric cancer enhances tumor-induced lymphangiogenesis
Smad-dependent pathway of TGF-β1 signaling. a LY2157299 suppressed the expression of phospho-Smad3 in KATOIII. b The change in p-Smad3 expression in response to TGF-β1 in the cytosol and nucleus. In KATOIII cells, the amount of nucleus p-Smad was increased in response to TGF-β1, while decreased in response to LY2157299. Lamin and GAPDH were used as a loading controls in the nucleus and cytosol, respectively