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Table 4 Subgroup analyses according to chemotherapy (P for interaction: 0.679)

From: Comparative effectiveness of primary tumor resection in patients with stage III pancreatic adenocarcinoma

 

No chemotherapy or unknown

Chemotherapy

OS

 Non-adjusted

0.58 (0.51, 0.65) < 0.001

0.67 (0.55, 0.81) < 0.001

 Adjusted

  Traditional regression model

0.58 (0.51, 0.66) < 0.001

0.61 (0.48, 0.76) < 0.001

  2SRI IV model

1.27 (0.51, 3.13) 0.610

0.43 (0.09, 2.15) 0.304

DSS

 Non-adjusted

0.55 (0.49, 0.63) < 0.001

0.67 (0.55, 0.82) < 0.001

 Adjusted

  Traditional regression model

0.56 (0.49, 0.64) < 0.001

0.61 (0.48, 0.77) < 0.001

  2SRI IV model

1.31 (0.51, 3.34) 0.573

0.56 (0.10, 3.14) 0.508

  1. PTR was the reference (HR: 1). Data are shown as HR (95%CI) P value. All adjusted models were adjusted for: age, race, sex, year of diagnosis, tumor location and tumor size. OS, overall survival; DSS, disease-specific survival; 2SRI, 2 stage residual inclusion; IV, instrumental variable