Table 3 Cox regression analysis for overall survival
From: High baseline Tie1 level predicts poor survival in metastatic breast cancer
N | n | Overall survival | ||||
|---|---|---|---|---|---|---|
Age-adjusted HR [95% CI] | p value | multivariate HRa [95% CI] | p value | |||
Baseline Tie1 | ||||||
Low | 27 | 15 | 1 | 1 | ||
High | 26 | 24 | 2.82 [1.41–5.66] | 0.003 | 3.07 [1.39–6.79] | 0.005 |
Baseline Ang2 | ||||||
Low | 27 | 15 | 1 | 1 | ||
High | 26 | 24 | 2.33 [1.20–4.54] | 0.012 | 1.58 [0.72–3.46] | 0.246 |
Combined analysis | ||||||
Tie1 and Ang2 low | 18 | 8 | 1 | 1 | ||
Tie1 low, Ang2 high | 9 | 7 | 2.21 [0.78–6.25] | 0.135 | 1.34 [0.42–4.22] | 0.612 |
Tie1 high, Ang2 low | 9 | 7 | 2.77 [0.95–8.09] | 0.062 | 2.73 [0.88–8.46] | 0.080 |
Tie1 and Ang2 high | 17 | 17 | 4.79 [1.93–11.90] | 0.001 | 4.32 [1.44–12.94] | 0.009 |