Skip to main content

Table 3 Cox regression analysis for overall survival

From: High baseline Tie1 level predicts poor survival in metastatic breast cancer

 NnOverall survival
Age-adjusted HR [95% CI]p valuemultivariate HRa [95% CI]p value
Baseline Tie1
 Low27151 1 
 High26242.82 [1.41–5.66]0.0033.07 [1.39–6.79]0.005
Baseline Ang2
 Low27151 1 
 High26242.33 [1.20–4.54]0.0121.58 [0.72–3.46]0.246
Combined analysis
 Tie1 and Ang2 low1881 1 
 Tie1 low, Ang2 high972.21 [0.78–6.25]0.1351.34 [0.42–4.22]0.612
 Tie1 high, Ang2 low972.77 [0.95–8.09]0.0622.73 [0.88–8.46]0.080
 Tie1 and Ang2 high17174.79 [1.93–11.90]0.0014.32 [1.44–12.94]0.009
  1. Abbreviations: N number of patients, n number of events, HR hazard ratio, CI confidence interval. Statistically significant results are highlighted in bold
  2. aHazard ratio adjusted by age, menopausal status, hormone receptor status, presence of visceral metastasis, number of metastatic lesions and extent of the disease