Table 2 Cox regression analysis for progression-free survival
From: High baseline Tie1 level predicts poor survival in metastatic breast cancer
N | n | Progression-free survival | ||||
|---|---|---|---|---|---|---|
Age-adjusted HR [95% CI] | p value | multivariate HRa [95% CI] | p value | |||
Baseline Tie1 | ||||||
Low | 27 | 16 | 1 | 1 | ||
High | 26 | 15 | 2.13 [1.02–4.46] | 0.043 | 3.78 [1.57–9.09] | 0.003 |
Baseline Ang2 | ||||||
Low | 27 | 14 | 1 | 1 | ||
High | 26 | 17 | 1.21 [0.59–2.47] | 0.597 | 1.22 [0.54–2.77] | 0.620 |
Combined analysis | ||||||
Tie1 and Ang2 low | 18 | 9 | 1 | 1 | ||
Tie1 low, Ang2 high | 9 | 7 | 1.27 [0.47–3.43] | 0.632 | 1.16 [0.39–3.39] | 0.783 |
Tie1 high, Ang2 low | 9 | 5 | 3.86 [1.18–12.57] | 0.025 | 4.45 [1.25–15.79] | 0.021 |
Tie1 and Ang2 high | 17 | 10 | 2.02 [0.80–5.07] | 0.133 | 3.88 [1.25–12.06] | 0.019 |