Fig. 4

Progression-free survival and overall survival grouped by combined analysis of baseline plasma Tie1 and baseline plasma Ang2 levels. a Progression-free survival and b Overall survival for patients with high or low baseline Tie1 and Ang2. Cox regression analysis adjusted by age, menopausal status, hormone receptor status, presence of visceral metastasis, number of metastatic lesions and extent of the disease. ^ap-value between Tie1 low, Ang2 low and Tie1 low, Ang2 high, ^bp-value between Tie1 low, Ang2 low and Tie1 high, Ang2 low, ^cp-value between Tie1 low, Ang2 low and Tie1 high, Ang2 high