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Fig. 2 | BMC Cancer

Fig. 2

From: Vasculogenic mimicry-associated ultrastructural findings in human and canine inflammatory breast cancer cell lines

Fig. 2

Transmission electron microscopy of IPC-366 (a, b) in adherent conditions (2D) and SUM149 (c, d, e, f) in non-adherent conditions (mammospheres). a and b: Endothelial-like cells (ELCs) in formation. Multiple empty cytoplasmic spaces (arrows), with microvilli covered by cytoplasmic membrane (insert) and nucleus margination. c, d and e: ELCs showing the characteristic morphology: a unique cytoplasmic empty space and eccentric nucleus. f: ELC cytoplasm with Weibel-Palade bodies (arrows). Original magnification; a, d) × 6,000, b) × 10,000, c) × 3,000, e) × 4,000, f) × 60,000

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