Fig. 5
From: microRNA-21 promotes breast cancer proliferation and metastasis by targeting LZTFL1
miR-21/LZTFL1 regulates β-catenin nuclear translocation and EMT process. a The protein levels of EMT markers in Hs578T cells treated with miR-21 inhibitor, LZTFL1 siRNA alone, or combined for 48 h. b The protein levels of EMT markers in Hs578T cells treated with miR-21 mimic, LZTFL1 overexpressing plasmid alone, or combined for 48 h. c and d Immunofluorescence microscopy analysis of β-catenin nuclear translocation in Hs578T cells following the treatments indicated in (a) and (b). e and f. Colocalization rate representing relativeβ-catenin nuclear translocation in (c) and (d). (*p < 0.05, **p < 0.01, ***p < 0.001)