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Table 2 Risk of distant relapse according to PLCγ1-pY1253 and PLCγ1-pY783 expression in Luminal-A and Luminal-B tumour subtypes depends on menopausal status. Multivariate analysis

From: PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes

Menopause statusTumour subtypePLCγ1-pY1253PLCγ1-pY783
HRa95% CIbPHRa95% CIbP
Pre/PerimenopausalLuminal A7.50.8–71.80.07920.12.2–178.40.003
Luminal B2.50.6–10.30.1952.90.7–12.20.149
PostmenopausalLuminal A2.20.5–9.40.2742.60.7–10.70.172
Luminal B2.41.1–5.30.0341.20.5–3.20.717
  1. aHR Hazard ratio (high versus low PLCγ1-pY expression)
  2. bCI Confidence interval; statistically significant p-values are formatted in bold