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Fig. 4 | BMC Cancer

Fig. 4

From: PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes

Fig. 4

Kaplan-Meier plots in Luminal-A and Luminal-B subtypes. Kaplan-Meier estimates of DRFS in patients with Luminal-A and Luminal-B tumours according to menopausal status. In Luminal-A tumours, the patients with postmenopausal status showed distant relapse in 5% (3/62) PLCγ1-pY1253Low and 11% (5/44) PLCγ1-pY1253High, and in 5% (4/82) PLCγ1-pY783Low and 17% (4/24) PLCγ1-pY783High, and the patients with premenopausal status showed distant relapse in 4% (1/28) PLCγ1-pY1253Low and 23% (5/22) PLCγ1-pY1253High, and in 0% (0/37) PLCγ1-pY783Low and 46% (6/13) PLCγ1-pY783High. In Luminal-B tumours, the patients with postmenopausal status showed distant relapse in 12% (9/76) PLCγ1-pY1253Low and 29% (18/63) PLCγ1-pY1253High, and in 20% (22/109) PLCγ1-pY783Low and 17% (5/30) PLCγ1-pY783High, and the patients with premenopausal status showed distant relapse in 17% (4/24) PLCγ1-pY1253Low and 31% (4/13) PLCγ1-pY1253High, and in 16% (5/31) PLCγ1-pY783Low and 50% (3/6) PLCγ1-pY783High

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