Fig. 1
From: Metformin reverses mesenchymal phenotype of primary breast cancer cells through STAT3/NF-κB pathways
Metformin-resistance correlates with mesenchymal phenotype in primary breast cancer cells. a MBCD3, MBCD23, MBCD-D5, MBCD-B3, MBCDF, MBCD17, MBCD25 primary breast cancer cell were treated with increasing concentrations of MTF and cell viability was analyzed by crystal violet after 48 h. Data represent the mean ± SEM of three independent experiments in triplicate incubations. *P < 0.001 epithelial versus mesenchymal from 1 to 100 mM MTF. b Representative immunoblot showing E-cadherin, Vimentin, and SNAIL EMT markers expression. Actin was used as loading control