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Table 5 Performance of 3 protein classifier. The cut-off was chosen (CEACAM5 > 4.92, WFDC2 > 75.57, TCL1A > 8.34) to best separate benign and cancer cases and LAC and CRC met cases

From: Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung

Signature vs Benign
 Specificity1.00Benign680True
 Sensitivity0.45Tumor7965outcome
 PPV1.00 Predicted outcome 
 NPV0.46    
 Accuracy0.63    
Signature vs CRC met
 Specificity0.82CRC met6815True
 Sensitivity0.45LAC7965Outcome
 PPV0.81 Predicted outcome 
 NPV0.46    
 Accuracy0.59    
  1. PPV Positive predictive value, NPV Negative predictive value, LAC Lung adenocarcinoma, CRC met colorectal metastasis