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Table 3 Comparison of single protein classifiers with median as cut-offa

From: Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung

CEACAM5
 Specificity1.00 LowHigh 
 Sensitivity0.26Benign680True
 PPV1.00LAC11331outcome
 NPV0.38 Predicted outcome 
 Accuracy0.47    
CXCL17
 Specificity0.66 LowHigh 
 Sensitivity0.60Benign4523True
 PPV0.79LAC5886outcome
 NPV0.44 Predicted outcome 
 Accuracy0.62    
VEGFR2  LowHigh 
 Specificity0.35Benign2444True
 Sensitivity0.40LAC8757outcome
 PPV0.56 Predicted outcome 
 NPV0.22    
 Accuracy0.38    
ERBB3  LowHigh 
 Specificity0.40Benign3654True
 Sensitivity0.44LAC8163outcome
 PPV0.54 Predicted outcome 
 NPV0.31    
 Accuracy0.42    
  1. aThe median protein level was used as cut-off (high vs low) to determine group affiliation
  2. PPV Positive predictive value, NPV Negative predictive value, LAC Lung adenocarcinoma