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Table 3 Univariate and multivariate analysis of 5-year overall survival

From: Preoperative systemic inflammation score (SIS) is superior to neutrophil to lymphocyte ratio (NLR) as a predicting indicator in patients with esophageal squamous cell carcinoma

Variables Univariate Multivariate
5-year OS P value (log-rank) Hazard ratio 95%CI P value
Gender   0.047    
 Male 279     
 Female 78     
Age (years)   0.159    
  ≤ 65 276     
  > 65 81     
T stage   < 0.001 1.323 1.12–1.53 0.008
 T1 40     
 T2 71     
 T3 209     
 T4 37     
N stage   < 0.001 1.525 1.4–1.65 < 0.001
 N0 155     
 N1 87     
 N2 69     
 N3 46     
Vascular invasion   <0.001    
 No 45     
 Yes 312     
Tumor cell   0.61    
 G1 54     
 G2 258     
 G2 45     
Tumor location   0.018 1.361 1.09–1.63 0.025
 Upper third 60     
 Middle third 260     
 Lower third 37     
Adjuvant CRT   0.036    
 Yes 214     
 No 143     
Tumor length   < 0.001 1.609 1.31–1.9 0.002
  ≤ 5 cm 236     
  > 5 cm 157     
SIS   < 0.001 1.24 1.05–1.43 0.029
 0 119     
 1 148     
 2 90     
NLR   0.006    
  ≤ 2.27 228     
 >2.27 129