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Table 3 Univariate and multivariate analysis of 5-year overall survival

From: Preoperative systemic inflammation score (SIS) is superior to neutrophil to lymphocyte ratio (NLR) as a predicting indicator in patients with esophageal squamous cell carcinoma

Variables

Univariate

Multivariate

5-year OS

P value (log-rank)

Hazard ratio

95%CI

P value

Gender

 

0.047

   

 Male

279

    

 Female

78

    

Age (years)

 

0.159

   

  ≤ 65

276

    

  > 65

81

    

T stage

 

< 0.001

1.323

1.12–1.53

0.008

 T1

40

    

 T2

71

    

 T3

209

    

 T4

37

    

N stage

 

< 0.001

1.525

1.4–1.65

< 0.001

 N0

155

    

 N1

87

    

 N2

69

    

 N3

46

    

Vascular invasion

 

<0.001

   

 No

45

    

 Yes

312

    

Tumor cell

 

0.61

   

 G1

54

    

 G2

258

    

 G2

45

    

Tumor location

 

0.018

1.361

1.09–1.63

0.025

 Upper third

60

    

 Middle third

260

    

 Lower third

37

    

Adjuvant CRT

 

0.036

   

 Yes

214

    

 No

143

    

Tumor length

 

< 0.001

1.609

1.31–1.9

0.002

  ≤ 5 cm

236

    

  > 5 cm

157

    

SIS

 

< 0.001

1.24

1.05–1.43

0.029

 0

119

    

 1

148

    

 2

90

    

NLR

 

0.006

   

  ≤ 2.27

228

    

 >2.27

129