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Table 2 ESCC Patients’ clinicopathological characteristics according to NLR and SIS

From: Preoperative systemic inflammation score (SIS) is superior to neutrophil to lymphocyte ratio (NLR) as a predicting indicator in patients with esophageal squamous cell carcinoma

characteristics NLR SIS groups
NLR ≤ 2.27 NLR > 2.27 P SIS = 0 SIS = 1 SIS = 2 P
N = 228 N = 129 N = 119 N = 148 N = 90
Gender    0.003     < 0.001
 Male 167 112   71 128 80  
 Female 61 17   48 20 10  
Age    0.874     0.087
  ≤ 65 years old 177 99   95 119 62  
 >65 years old 51 30   24 29 28  
Vascular Invasiona    0.453     0.944
 No 197 115   103 130 79  
 Yes 31 14   16 18 11  
Tumor cell differentiationa    0.561     0.412
 G1 31 23   14 21 15  
 G2 168 90   90 109 18  
 G3 29 16   15 18 12  
Tumor locationa    0.728     0.324
 Upper 41 16   21 26 7  
 Middle 164 96   91 105 17  
 Lower 23 14   7 64 13  
Tumor length    < 0.001     0.004
  ≤ 5 cm 167 69   91 98 49  
  > 5 cm 61 60   28 50 41  
T stage    0.002     0.102
 T1 33 7   18 14 8  
 T2 53 18   26 34 11  
 T3 124 85   60 89 60  
 T4 18 19   15 11 11  
N stage    0.266     0.161
 N0 104 51   58 65 32  
 N1–3 124 78   61 83 58  
Stage    0.109     0.117
 I 24 5   14 12 3  
 II 81 24   43 51 29  
 III 90 59   49 61 39  
 IVa 33 23   13 24 19  
  1. a While N ≥ 40 and 1 ≤ theoretical frequency(T)<5, the Fisher exact test was used to compare the influencing factors