Preoperative systemic inflammation score (SIS) is superior to neutrophil to lymphocyte ratio (NLR) as a predicting indicator in patients with esophageal squamous cell carcinoma

Table 2 ESCC Patients’ clinicopathological characteristics according to NLR and SIS

characteristics	NLR			SIS groups
	NLR ≤ 2.27	NLR > 2.27	P	SIS = 0	SIS = 1	SIS = 2	P
	N = 228	N = 129	P	N = 119	N = 148	N = 90	P
Gender			0.003				< 0.001
Male	167	112		71	128	80
Female	61	17		48	20	10
Age			0.874				0.087
≤ 65 years old	177	99		95	119	62
>65 years old	51	30		24	29	28
Vascular Invasion^a			0.453				0.944
No	197	115		103	130	79
Yes	31	14		16	18	11
Tumor cell differentiation^a			0.561				0.412
G1	31	23		14	21	15
G2	168	90		90	109	18
G3	29	16		15	18	12
Tumor location^a			0.728				0.324
Upper	41	16		21	26	7
Middle	164	96		91	105	17
Lower	23	14		7	64	13
Tumor length			< 0.001				0.004
≤ 5 cm	167	69		91	98	49
> 5 cm	61	60		28	50	41
T stage			0.002				0.102
T1	33	7		18	14	8
T2	53	18		26	34	11
T3	124	85		60	89	60
T4	18	19		15	11	11
N stage			0.266				0.161
N0	104	51		58	65	32
N1–3	124	78		61	83	58
Stage			0.109				0.117
I	24	5		14	12	3
II	81	24		43	51	29
III	90	59		49	61	39
IVa	33	23		13	24	19

^a While N ≥ 40 and 1 ≤ theoretical frequency(T)<5, the Fisher exact test was used to compare the influencing factors

ISSN: 1471-2407