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Table 1 Baseline information of included studies for glioma diagnosis

From: Diagnostic and grading accuracy of 18F-FDOPA PET and PET/CT in patients with gliomas: a systematic review and meta-analysis

Reference

Year

Country

Design

Specimens No.

Patients No.

Age, yr

M/F

Test

Prior treatment

Occurrence

Gold Standard

Meana

Median

Chen et al. [9]

2006

US

Prospective

27

30 (27b)

–

–

–

PET

With or without

7 New+ 20 Recur

Histo+Radio+follow-up

Tripathi et al. [10]

2009

India

Prospective

15

15

28.4 ± 11.1

–

9/6

PET/CT

With (Sx/CT/RT) or without

3 New+ 12 Recur

Histo+Radio+follow-up

Sellam et al. [22]

2010

India

Prospective

30

30

–

–

–

PET/CT

Sx+/−RT

Recur

Histo+Radio+follow-up

Jora et al. [23]

2011

India

Prospective

23

23

43.25 ± 14.9

–

–

PET/CT

15 with (Sx + RT) + 8 without

8 New+ 15 Recur

Histo+Radio+follow-up

Karunanithi et al. [15]

2013

India

Prospective

35

35

36.62 ± 0.86

–

28/7

PET/CT

Sx + RT+/−CT

Recur

Histo+Radio+follow-up

Pafundi et al. [24]

2013

US

Prospective

23

10

40.8 ± 18.9

–

9/1

PET/CT

With or without

8 New+ 2 Recur

Histo

Herrmann et al. [25]

2014

US

Retrospective

110

110

51.7 ± 12.1

52.5

72/38

PET/CT

Sx

Recur

Histo+Radio+follow-up

Moran et al. [26]

2015

Italy

Retrospective

27

27

10

10

15/12

PET

1 with (Sx + CT + RT) + 20 without

20 New+ 1 Recur

Histo+Radio+follow-up

Sharma et al. [27]

2016

India

Prospective

12

11

34

–

6/5

PET/CT

Sx

Recur

Histo+Radio+follow-up

Paquet et al. [28]

2017

France

Prospective

60

35

60

–

–

PET

Sx + CT + RT

Recur

Histo+Radio

Evangelista et al. [29]

2018

Italy

Retrospective

13

13

–

60

–

PET/CT

Unclear

Recur

Radio+follow-up

Youland et al. [30]

2018

US

Prospective

37

13

–

40

9/4

PET

Sx/CT/RT

Recur

Histo

Evangelista et al. [31]

2019

Italy

Retrospective

21

21

58 ± 11

–

–

PET/CT

Sx + CT/RT/immunotherapy

Recur

Radio+follow-up

  1. M male, F female, New newly-diagnosed, Recur recurrent, Histo histopathology, Radio radiology, Sx surgery, CT chemotherapy, RT radiation therapy
  2. aMean age is expressed as mean ± standard deviation
  3. bThree patients with brain metastases were excluded