Volumetric parameters on 18F-FDG PET/CT predict the survival of patients with gastric cancer associated with their expression status of c-MET

Table 5 Multivariate linear COX regression assessing associations between parameters from ¹⁸F-FDG PET/CT and prognosis in patients with positive c-Met expression

Variables	PFS^b		PFS^c		OS^b		OS^c
Variables	HR	P	HR	P	HR	P	HR	P
Findings on PET/CT
Distant metastasis	5.620	< 0.001	5.650	< 0.001	3.026	0.002	3.151	0.002
Locoregional^a	1.000		1.000		1.000		1.000
SUV_max	0.819	0.582	0.788	0.510	1.306	0.530	1.268	0.486
SUV_peak	1.313	0.558	1.372	0.498	0.727	0.552	0.761	0.537
MTV	1.005	0.274			1.009	0.024
TLG			1.001	0.350			1.003	0.021

Note. PET/CT positron emission tomography/computed tomography, SUV standardized uptake value, Max maximum, MTV metabolic tumor volume, TLG total lesion glycolysis, PFS progression free survival, OS overall survival, HR hazards ratio. ^a, reference group. ^b This model used MTV, not TLG. ^c This model used TLG, not MTV

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