Fig. 4
Low miR-1275 expression and high JAZF1 expression correlate with metastasis and poor survival in GC patients. a and bExpression of miR-1275 and JAZF1 in 120 pairs of samples from GC patients with and without metastasis and classified as either Borrmann type I + II or Borrmann type III + IV. The expression levels were determined by qRT-PCR and normalized to that of an endogenous control (U6 RNA). The data were analysed using the formula 2-ΔCT. c Inverse correlation of miR-1275 expression with JAZF1 mRNA expression in paired samples from 120 GC patients (P = 0.013, r = − 0.271, χ2 test). d and e qRT-PCR analysis of miR-1275 expression in different lymph node types from GC patient samples from the TCGA database. f Kaplan-Meier analysis of OS of GC patients according to the miR-1275 and JAZF1 mRNA expression profiles (left: TCGA database)