Table 1 Crude and adjusted ORs of age and FIT variables for association with ACN in the derivation (Phase I) cohort (Seminal model: C-Statistic = 0.846; Brier Score = 0.115; Hosmer-Lemeshow p-value = 0.796)
X | Control group (non-AA, non-CRC) | AA+CRC | OR (Crude) | OR (Adjusted) |
|---|---|---|---|---|
Age group (years) | ||||
≤ 40 | 66 (9.48%) | 1 (0.58%) | Ref. | Ref. |
40–50 | 98 (14.1%) | 6 (3.51%) | 3.61 [0.58;94.9] | 4.62 [0.49;43.6] |
50–60 | 157 (22.6%) | 34 (19.9%) | 12.5 [2.63;299] | 17.9 [2.25;142.4] |
> 60 | 375 (53.9%) | 130 (76.0%) | 20.0 [4.42;469] | 21.54 [2.8;165.6] |
MAXFIT (out of 3 samples) | ||||
≤ 11 | 508 (73.0%) | 33 (19.3%) | Ref. | Ref. |
> 11 | 188 (27.0%) | 138 (80.7%) | 11.2 [7.49;17.3] | 2.31 [0.99;5.38] |
NSAMPLES> 4 | ||||
0 | 441 (63.4%) | 24 (14.0%) | Ref. | Ref. |
1 | 110 (15.8%) | 18 (10.5%) | 3.01 [1.55;5.74] | 2.98 [1.54;5.8] |
2 | 71 (10.2%) | 18 (10.5%) | 4.65 [2.37;9.01] | 4.49 [2.3;8.8] |
3 | 74 (10.6%) | 111 (64.9%) | 27.2 [16.7;46.0] | 28.1 [16.8;46.9] |