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Table 1 Crude and adjusted ORs of age and FIT variables for association with ACN in the derivation (Phase I) cohort (Seminal model: C-Statistic = 0.846; Brier Score = 0.115; Hosmer-Lemeshow p-value = 0.796)

From: Prediction of advanced colonic neoplasm in symptomatic patients: a scoring system to prioritize colonoscopy (COLONOFIT study)

XControl group (non-AA, non-CRC)AA+CRCOR (Crude)OR (Adjusted)
Age group (years)
  ≤ 4066 (9.48%)1 (0.58%)Ref.Ref.
 40–5098 (14.1%)6 (3.51%)3.61 [0.58;94.9]4.62 [0.49;43.6]
 50–60157 (22.6%)34 (19.9%)12.5 [2.63;299]17.9 [2.25;142.4]
  > 60375 (53.9%)130 (76.0%)20.0 [4.42;469]21.54 [2.8;165.6]
MAXFIT (out of 3 samples)
  ≤ 11508 (73.0%)33 (19.3%)Ref.Ref.
  > 11188 (27.0%)138 (80.7%)11.2 [7.49;17.3]2.31 [0.99;5.38]
NSAMPLES> 4
 0441 (63.4%)24 (14.0%)Ref.Ref.
 1110 (15.8%)18 (10.5%)3.01 [1.55;5.74]2.98 [1.54;5.8]
 271 (10.2%)18 (10.5%)4.65 [2.37;9.01]4.49 [2.3;8.8]
 374 (10.6%)111 (64.9%)27.2 [16.7;46.0]28.1 [16.8;46.9]
  1. MAXFIT: maximum f-Hb value; NSAMPLES > 4: Number of samples with FIT > 4 μg Hb/g faeces